Muscle Loss Can Start Around 30, Long Before Most People Think About It
Preston, England, UK, October 2026 — NovusDNA, a UK-based longevity supplement brand, says the longevity conversation has become almost entirely about what happens inside a cell: biomarkers, cellular energy, molecular ageing pathways. A more basic form of ageing gets far less attention, particularly from people in their 40s and 50s: the slow loss of muscle, which begins years before there is any visible sign of it.
The Years Most People Miss
A review published in Current Opinion in Clinical Nutrition and Metabolic Care puts muscle loss at roughly 3 to 8% per decade after the age of 30, with the rate rising after 60. Someone in their 40s or 50s may therefore already be years into a process that gives little warning.
The encouraging part is that muscle stays responsive. The same review describes aged muscle as “still very plastic”, able to increase in mass and strength in response to training. The case for paying attention in midlife is therefore not that a window is closing. It is that starting earlier simply means there is more to protect.
“Nobody in their 40s or 50s feels like they urgently need to think about muscle loss, because nothing about it feels urgent at that age, and that’s exactly the problem,” said Julie Dawson, Director at NovusDNA. “The loss can already be underway by then, and it’s quiet. The good news is that muscle keeps responding to training well into older age, so the sensible time to start looking after it is before you can feel the difference, not after.”
Why NovusDNA Treats This as a Starting Point, Not a Later-Life Fix
Researchers have looked specifically at creatine alongside resistance training in older adults. A 2025 meta-analysis of eight randomised trials in adults with an average age of 50 or over found a significant improvement in lean tissue mass when creatine was combined with resistance training. The certainty of the evidence for muscle mass was rated low, while effects on strength varied by outcome, with a borderline significant improvement in lower-limb strength but no significant overall difference in upper-limb strength.
The research does not suggest that creatine replaces resistance training. Instead, it has been studied as an addition to it, particularly in older populations. The evidence in adults in their early 40s is less directly established, which is an important distinction for a brand built around following what the research actually shows.
That distinction also shapes how NovusDNA positions its Micronised Creatine Monohydrate: not as a solution to age-related muscle loss, but as a well-studied supplement that can sit alongside the fundamentals of maintaining muscle and strength, including resistance training. The product is independently tested for purity by Campden BRI, a UKAS-accredited laboratory, with testing results made available by NovusDNA.
Muscle is also only one part of structural ageing. Bone changes across a similar period of life. The American Academy of Orthopaedic Surgeons notes that most people reach peak bone mass between 25 and 30 and begin to lose bone mass slowly by around 40.
NovusDNA’s Structural Health Stack combines collagen with Vitamin D3, K2 and magnesium, for people who want to look after the bone and connective-tissue side of the picture alongside the muscle side, rather than treating it as a separate purchase.
“We built NovusDNA around following the evidence rather than the trend, and the evidence says muscle loss starts earlier than many people expect,” Julie said. “We’d rather meet someone while it’s still easy to stay ahead of than wait until it’s a recovery project.”
NovusDNA believes muscle, strength and functional ability should be part of the longevity conversation in people’s 40s and 50s, rather than something that only enters the picture in their 70s and 80s.
This press release is for informational purposes only. NovusDNA supplements are not intended to diagnose, treat, cure or prevent any disease. Research cited is drawn from published peer-reviewed studies and reviews and from publicly available health guidance. Study findings relate to the populations studied and do not predict individual results.
About NovusDNA
NovusDNA is a UK-based longevity supplement brand focused on evidence-informed, third-party tested formulations designed to support cellular health, metabolic function and long-term wellbeing. The company takes an education-first approach to supplementation, helping consumers make more informed decisions in a market increasingly shaped by scientific literacy and transparency. Its range is available at novusdna.com.
Media Contact
Company: NovusDNA: novusdna.com
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City/Country: Preston, England, United Kingdom
Disclaimer: This article is intended for informational and educational purposes only. It discusses age-related muscle loss and general ways to support muscle health. The information provided should not be considered medical advice or a substitute for professional consultation. Individual results may vary, and readers should consult a qualified healthcare professional for personalized guidance.